I. Community Acquired,
   Non-ICU Admission

(choose one of two options)

Option 1

Ceftriaxone [ROCEPHIN] 1 gm IV ONCE
  &
Azithromycin [ZITHROMAX] 500 mg IV ONCE

Option 2

Levofloxacin [LEVAQUIN] 750 mg IV ONCE

II. Community Acquired,
     ICU Admission

(choose one of three options)

Option 1

Ceftriaxone [ROCEPHIN] 1gm IV ONCE
  &
Azithromycin [ZITHROMAX] 500 mg IV ONCE

Option 2

Ceftriaxone [ROCEPHIN] 1 gm IV ONCE
  &
Levofloxacin [LEVAQUIN] 750 mg IV ONCE

~

If severe Penicillin allergy or any cephalosporin allergy

Option 3

Levofloxacin [LEVAQUIN] 750 mg IV ONCE
  &
Aztreonam [AZACTAM] 1 2  gm IV ONCE

III. Community Acquired w/
      Pseudomonas Risk or
      HCAP (includes both ICU
      + Non ICU)

(choose one of five options
 +/- vancomycin)

Option 1

Cefepime [MAXIPIME] 1 2  gm IVPB ONCE
  &
Levofloxacin [LEVAQUIN] 750 mg IV ONCE

Option 2

Piperacillin-Tazobactam [ZOSYN] 4.5 3.375 2.25 GM IV ONCE
  &
Levofloxacin [LEVAQUIN] 750 mg IV ONCE

Option 3

Meropenem [MERREM] 500 mg IV ONCE
  &
Levofloxacin [LEVAQUIN] 750 mg IV ONCE

~

If Levaquin Contraindicated

Option 4

Cefepime [MAXIPIME] 1 2  gm IVPB ONCE
  &
Azithromycin [ZITHROMAX] 500 mg IV ONCE
  &
Tobramycin [NEBCIN] 5mg/Kg IV ONCE

Option 5

Piperacillin-Tazobactam [ZOSYN] 4.5 3.375 2.25 GM IV ONCE
  &
Azithromycin [ZITHROMAX] 500 mg IV ONCE
  &
Tobramycin [NEBCIN] 5mg/Kg IV ONCE

Option 6

Meropenem [MERREM] 500 mg IV ONCE
 &
Azithromycin [ZITHROMAX] 500 mg IV ONCE
  &
Tobramycin [NEBCIN] 5mg/Kg IV ONCE

~

If severe Penicillin allergy or any cephalosporin allergy

Option 7

Aztreonam [AZACTAM] 1 2 gm IV ONCE
  &
Levofloxacin [LEVAQUIN] 750 mg IV ONCE
 Tobramycin 5mg/Kg IV ONCE

~

(plus, for HCAP patients)

Clindamycin [CLEOCIN] 600 mg IV ONCE, for Anaerobic Coverage

Vancomycin [VANCOMYCIN] 20mg/Kg IV ONCE

Linezolid [ZYVOX] 600 mg IV ONCE

Azithromycin [ZITHROMAX] 500 mg IV ONCE